Properties and features
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Polyoxidonium affects the body in a complex way:

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1
strengthens local immunity and enhances protection against bacterial, viral, and fungal infections.
2
It increases the efficiency of systemic immunity. This helps the body fight viruses, bacteria and fungi.
3
It eliminates harmful substances that accumulate in the body due to viruses. This helps to get rid of the ARVI symptoms — fever, headache, rheumatic pain in a faster way.
4
It reduces the level of inflammatory processes. Not only the severity of a disease is reduced, but the risk of complications after influenza and ARVI as well.

According to the results of international safety studies of the drug, Polyoxidonium is included in the clinical recommendations on the treatment not only in Russia, but also in Slovakia.

Its high safety profile is manifested by the fact that:

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It is a chemically pure drug
It does not contain any antigens of animal or plant origin, which means that it can be used for the treatment of patients with allergies.
The active ingredient of Polyoxidonium is AZOXIMER BROMIDE
It is well tolerated and does not irritate mucous membranes, so it can be used even for the treatment of very young children aged from 1 year.
Azoximer bromide is used as an adjuvant
An adjuvant is a compound that enhances the immune response. Azoximer bromide is used as such in a number of vaccines, for example, in Grippol. The fact that the ingredient is added to vaccines to enhance their action serves as one of the indicators of the safety and efficacy of the drug.
The drug does not accumulate
The active ingredient is completely eliminated from the body, and after 3–4 months new courses of treatment are possible.
Polyoxidonium increases reduced immunity parameters
At the same time, it does not affect the normal ones, which means that a patient is not threatened by hyperactivation of the immune system.

Polyoxidonium is used to treat a wide range of diseases. It is used in the treatment of ARVI, including influenza (the drug is recommended by the Federal Medical-Biological Agency, is specified in the clinical recommendations of the Ministry of Health of the Russian Federation). The drug is also used to treat inflammatory infections of the oropharynx, paranasal sinuses, upper respiratory tract, inner and middle ear, as well as to prevent immunodeficiencies.

The drug is also used as part of complex therapy to treat the coronavirus infection, allergies complicated by bacterial, viral or fungal infection, as well as inflammatory infections of the genitourinary system and female genital organs.

When using any drug, it is important to choose the right form and observe the dosage. Polyoxidonium is available in different forms: tablets and suppositories.
Polyoxidonium tablets
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One tablet contains 12 mg of the active ingredient — azoximer bromide. This form is suitable for the prevention and treatment of ARVI and influenza, and the tablets can also be prescribed by doctors — ENT specialists, pulmonologists, allergists or immunologists. Tablets can be taken by children and adults.

Treatment of influenza and ARVI
Dosage Duration of administration
Children from 3 to 10 years old 1/2 tablet 2 times a day 7 days
Children over 10 years old and adults 1 tablet 2 times a day 7 days
Prevention of influenza and ARVI
Dosage Duration of administration
Children from 3 to 10 years old 1/2 tablet 1 time a day 7 days
Children over 10 years old 1 tablet 1 time a day 7 days
Adults 1 tablet 1 time a day 10 days

Take the drug 20–30 minutes before meals without drinking water with it. Place the tablet under your tongue and hold it there until dissolved. This way, the drug can activate local immunity and increase the bactericidal properties of saliva, providing additional protection against infections.

More details about the dosage and duration of use of Polyoxidonium tablets to treat other diseases can be found in the package insert.

Contraindications

to taking Polyoxidonium in tablet form
Hypersensitivity to the components of the drug, lactose intolerance, pregnancy and breastfeeding, acute renal failure, age less than 3 years.
Polyoxidonium suppositories
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When using azoximer bromide in rectal and vaginal suppositories, the maximum concentration of the active ingredient in the body is reached already in an hour after taking the drug.

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Children’s suppositories

Dosage — 6 mg

Administered rectally in patients over 1 year of age. The treatment regimen is shown in the table:

Dosage Course of treatment
Prevention and treatment of influenza and ARVI and acute infectious diseases For children under 6 years of age — 1 suppository 1 time a day every other day; over 6 years of age — 1 suppository 1 time a day The course of treatment for children under 6 years of age is 5 suppositories; over 6 years of age — 10 suppositories
Exacerbation of chronic infectious diseases For children under 6 years of age — 1 suppository 1 time a day, the first three doses every other day, then increase the interval between doses up to 3 days. Course of treatment — 5 suppositories For children over 6 years of age — 1 suppository 1 time a day daily for 3 days, then every other day. Course of treatment — 10 suppositories
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Adults’ suppositories

Dosage — 12 mg

Administered rectally, in gynecological diseases — vaginally. The treatment regimen is shown in the table:

Dosage Course of treatment
Prevention and treatment of influenza and ARVI, exacerbation of urological diseases 1 suppository daily 10 suppositories
Gynecological diseases, exacerbation of chronic infectious diseases One suppository daily for the first 3 days, then one suppository every other day 10 suppositories

More details on the use of Polyoxidonium suppositories can be found in the package insert.

Contraindications

to taking Polyoxidonium in suppository form
hypersensitivity to any of the drug components, pregnancy and breastfeeding, acute renal failure, as well as children under 1 year of age. Very rare side effects of the drug may occur: redness, swelling or itching of the perianal area, vaginal itching. These effects may be caused by hypersensitivity to components of the drug. In case of an allergic reaction you should stop taking the drug and consult your doctor.

Any medications, including over-the-counter medications, should be taken in strict accordance with the instructions. If adverse reactions occur or if your condition worsens, you should consult your doctor.

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